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22815 Latex Specific IgE Panel (401468)

Latex Specific IgE Panel (401468)
Test Code: LATEX
Synonyms/Keywords
​Ammoniated Latex Extract, Buffered Latex, Glove Latex Extract
Test Components
​Ammoniated Latex Extract, Buffered Latex, Glove Latex Extract
Useful For
​This panel of latex specific IgE tests relies on the following three latex antigen preparations to aid in the identification of patients sensitive to natural rubber products: 1)Ammoniated Latex: Proteins were isolated from Malaysian H. brasiliensis latex collected in ammonia, the form usually used to manufacture dipped products. 2) Non-Ammoniated Latex (NAL) or Buffered Latex: To preserve the antigenic integrity of all proteins, latex was collected in a neutral pH buffer using the method developed by the FDA to prepare reference extracts. 3) Glove Latex: An aqueous extract was prepared from a commercial latex exam glove
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum ​Red Top Tube (RTT) ​ ​2 mL ​1 mL ​
Specimen Stability Information
Specimen Type Temperature
​Serum Ambient, refrigerated or frozen
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Viracor-IBT ​Tuesday ​5-7 days ​Radioimmunoassay
Reference Lab
Viracor Eurofins
Reference Range Information
Performing Location Reference Range
​Viracor-IBT ​Ammoniated Latex Extract (AL): <5 U/mL.
Buffered Latex (NAL): <5 U/mL.
Glove Latex Extract: <5 U/mL.
Interpretation
​If any of the antigens are positive then the patient is at risk if exposed via a parenteral or mucosal route to any natural rubber product in a surgical, dental, or diagnostic procedure. Patients with a positive history of a prior anaphylactic reaction should avoid Latex products, even if they are negative for IgE by any in vitro or in vivo method. This test was developed by IBT Reference Lab and was first reported at the International Latex Conference, November 5, 1992. The following classes are provided as a guide in ranking immunologic sensitivity:
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86003 ​ ​3 ​Allergen specific IgE ​
Synonyms/Keywords
​Ammoniated Latex Extract, Buffered Latex, Glove Latex Extract
Test Components
​Ammoniated Latex Extract, Buffered Latex, Glove Latex Extract
Ordering Applications
Ordering Application Description
​Centricity ​Latex Spec IgE Panel
​Cerner ​Allergen, Latex (401468)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum ​Red Top Tube (RTT) ​ ​2 mL ​1 mL ​
Specimen Stability Information
Specimen Type Temperature
​Serum Ambient, refrigerated or frozen
Useful For
​This panel of latex specific IgE tests relies on the following three latex antigen preparations to aid in the identification of patients sensitive to natural rubber products: 1)Ammoniated Latex: Proteins were isolated from Malaysian H. brasiliensis latex collected in ammonia, the form usually used to manufacture dipped products. 2) Non-Ammoniated Latex (NAL) or Buffered Latex: To preserve the antigenic integrity of all proteins, latex was collected in a neutral pH buffer using the method developed by the FDA to prepare reference extracts. 3) Glove Latex: An aqueous extract was prepared from a commercial latex exam glove
Test Components
​Ammoniated Latex Extract, Buffered Latex, Glove Latex Extract
Reference Range Information
Performing Location Reference Range
​Viracor-IBT ​Ammoniated Latex Extract (AL): <5 U/mL.
Buffered Latex (NAL): <5 U/mL.
Glove Latex Extract: <5 U/mL.
Interpretation
​If any of the antigens are positive then the patient is at risk if exposed via a parenteral or mucosal route to any natural rubber product in a surgical, dental, or diagnostic procedure. Patients with a positive history of a prior anaphylactic reaction should avoid Latex products, even if they are negative for IgE by any in vitro or in vivo method. This test was developed by IBT Reference Lab and was first reported at the International Latex Conference, November 5, 1992. The following classes are provided as a guide in ranking immunologic sensitivity:
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Viracor-IBT ​Tuesday ​5-7 days ​Radioimmunoassay
Reference Lab
Viracor Eurofins
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86003 ​ ​3 ​Allergen specific IgE ​
For most current information refer to the Marshfield Laboratory online reference manual.