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23249 Bupropion, Serum (178)

Bupropion, Serum (178)
Test Code: BUPRSO
Synonyms/Keywords
Wellbutrin®; Zyban®
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ ​Red Top Tube (RTT) ​ ​3 mL ​1 mL ​
​Plasma ​Lithium-heparin Green Top Tube or Sodium-heparin Green Top Tube (GTT) ​ ​3 mL ​1 mL ​
Collection Processing Instructions
Trough levels are most reproducible
 
The centrifuged specimen must be frozen immediately in a special transfer tube, available in Marshfield Labs Specimen Processing Department.  Outreach and Regional Centers please contact Marshfield Labs Customer Service at 800-222-5835 to request "transfer tube for Bupropion analysis".  Transfer tubes are ordered and stored by Marshfield Labs Specimen Processing.       
Specimen Stability Information
Specimen Type Temperature
​Serum or Plasma
Freeze immediately; ship frozen on dry ice.
Rejection Criteria
Serum Separator Tube (SST) Not Acceptable
​Plain transfer tube ​Not Acceptable
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Medtox Laboratories​ Performed Monday through Friday​ ​3 days
High Performance Liquid Chromatography with Ultraviolet Detection; (HPLC-UV)
Reference Lab
Medtox Laboratories
Reference Range Information
Reference Range
Bupropion, ng/ml
Report Limit
10 ng/ml
Reference Range
50 - 100 ng/ml
Critical Value - High
300 ng/ml
 
Hydroxybupropion, ng/ml
Report Limit
200 ng/ml
Reference Range
600 - 2000 ng/ml
Message
Note: Expected concentration range for hydroxybupropion: 600 - 2000 ng/ml.

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​80338 ​ ​ ​ ​
Synonyms/Keywords
Wellbutrin®; Zyban®
Ordering Applications
Ordering Application Description
​Centricity ​Bupropion, Serum SO (178)
​Cerner ​Bupropion, Serum SO (178)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ ​Red Top Tube (RTT) ​ ​3 mL ​1 mL ​
​Plasma ​Lithium-heparin Green Top Tube or Sodium-heparin Green Top Tube (GTT) ​ ​3 mL ​1 mL ​
Collection Processing
Trough levels are most reproducible
 
The centrifuged specimen must be frozen immediately in a special transfer tube, available in Marshfield Labs Specimen Processing Department.  Outreach and Regional Centers please contact Marshfield Labs Customer Service at 800-222-5835 to request "transfer tube for Bupropion analysis".  Transfer tubes are ordered and stored by Marshfield Labs Specimen Processing.       
Specimen Stability Information
Specimen Type Temperature
​Serum or Plasma
Freeze immediately; ship frozen on dry ice.
Rejection Criteria
Serum Separator Tube (SST) Not Acceptable
​Plain transfer tube ​Not Acceptable
Reference Range Information
Reference Range
Bupropion, ng/ml
Report Limit
10 ng/ml
Reference Range
50 - 100 ng/ml
Critical Value - High
300 ng/ml
 
Hydroxybupropion, ng/ml
Report Limit
200 ng/ml
Reference Range
600 - 2000 ng/ml
Message
Note: Expected concentration range for hydroxybupropion: 600 - 2000 ng/ml.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Medtox Laboratories​ Performed Monday through Friday​ ​3 days
High Performance Liquid Chromatography with Ultraviolet Detection; (HPLC-UV)
Reference Lab
Medtox Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​80338 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.