Positive: any specimen satisfying 1 of the following criteria.
-Four or more cells with gains of 2 or more chromosomes
-Ten or more cells with a gain of a single chromosome or 10 or more cells with tetrasomic signal patterns (ie, 4 copies for each of the 4 probes)
-Homozygous deletion of the 9p21 locus in > or =20% of the cells analyzed
For cases that are positive, the percentage of abnormal cells and type of chromosomal abnormality (ie, polysomy, trisomy, tetrasomy, or homozygous 9p21 deletion) are indicated in the test report.
Negative:
-Fewer than 4 cells with gains of 2 or more chromosomes
-Fewer than 10 cells with gain of a single chromosome or tetrasomy
-Less than 20% of cells with homozygous 9p21 deletion