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25246 Anser IFX, Prometheus (3150)

Anser IFX, Prometheus (3150)
Test Code: PIFXSO
Synonyms/Keywords
​Infliximab, Human Antichimeric Antibody (HACA)
Useful For

​Serum concentrations of infliximab (IFX) may vary among equally dosed patients which can ultimately affect patient outcomes.  Suboptimal levels of IFX have been lined to lower response rates in IBD patients.  Furthermore, some patients may develop immunogenicity to IFX by producing antibodies to infliximab (ATI).  The presence of ATI has also been associated with increased rates of infusion reasctions and drug clearance leading to lower response rates. 

The Anser IFX test is a next generation quantitative infliximab monitoring assay that measures and monitors serum IFX and ATI levels at anytime during therapy. 

Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Serum Separator Tube (SST) ​Red Top Tube (RTT) 2.0 mL ​0.5 mL ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Ambient ​7 days
​Refrigerate ​7 days
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​3 days ​Quantitative Chemistry Assay
Reference Lab
Prometheus Biosciences
Reference Range Information

Serum infliximab (IFX) concentration: <1.0 ug/mL

Antibody to infliximab (ATI) concentration: <3.1 U/mL

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​84999 ​ ​ ​ ​
Synonyms/Keywords
​Infliximab, Human Antichimeric Antibody (HACA)
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Serum Separator Tube (SST) ​Red Top Tube (RTT) 2.0 mL ​0.5 mL ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Ambient ​7 days
​Refrigerate ​7 days
Useful For

​Serum concentrations of infliximab (IFX) may vary among equally dosed patients which can ultimately affect patient outcomes.  Suboptimal levels of IFX have been lined to lower response rates in IBD patients.  Furthermore, some patients may develop immunogenicity to IFX by producing antibodies to infliximab (ATI).  The presence of ATI has also been associated with increased rates of infusion reasctions and drug clearance leading to lower response rates. 

The Anser IFX test is a next generation quantitative infliximab monitoring assay that measures and monitors serum IFX and ATI levels at anytime during therapy. 

Reference Range Information

Serum infliximab (IFX) concentration: <1.0 ug/mL

Antibody to infliximab (ATI) concentration: <3.1 U/mL

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​3 days ​Quantitative Chemistry Assay
Reference Lab
Prometheus Biosciences
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​84999 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.