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25300 Allergen, Ovomucoid, IgE (OVMU)

Allergen, Ovomucoid, IgE (OVMU)
Test Code: ALOVMSO
Useful For
Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
 
Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ ​Serum ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​0.5 mL 0.3 mL​ ​
Specimen Stability Information
Specimen Type Temperature Time
Serum ​Refrigerated (preferred) ​14 days
​ ​Frozen ​90 days
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories Monday through Saturday​ ​Same day/1 day Fluorescence Enzyme Immunoassay (FEIA)​
Reference Lab
Mayo Clinic Laboratories
Test Information
Clinical manifestations of immediate hypersensitivity (allergic) diseases are caused by the release of proinflammatory mediators (histamine, leukotrienes, and prostaglandins) from immunoglobulin E (IgE)-sensitized effector cells (mast cells and basophils) when cell-bound IgE antibodies interact with allergen.
 
In vitro serum testing for IgE antibodies provides an indication of the immune response to allergen(s) that may be associated with allergic disease.
 
The allergens chosen for testing often depend upon the age of the patient, history of allergen exposure, season of the year, and clinical manifestations. In individuals predisposed to develop allergic disease(s), the sequence of sensitization and clinical manifestations proceed as follows: eczema and respiratory disease (rhinitis and bronchospasm) in infants and children less than 5 years due to food sensitivity (milk, egg, soy, and wheat proteins) followed by respiratory disease (rhinitis and asthma) in older children and adults due to sensitivity to inhalant allergens (dust mite, mold, and pollen inhalants).​
Reference Range Information
Class
IgE kU/L
Interpretation
0
<0.35
Negative
1
0.35-0.69
Equivocal
2
0.70-3.49
Positive
3
3.50-17.4
Positive
4
17.5-49.9
Strongly positive
5
50.0-99.9
Strongly positive
6
> or =100
Strongly positive
Interpretation
Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
 
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86008 ​ ​ ​ ​
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ ​Serum ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​0.5 mL 0.3 mL​ ​
Specimen Stability Information
Specimen Type Temperature Time
Serum ​Refrigerated (preferred) ​14 days
​ ​Frozen ​90 days
Useful For
Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
 
Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens
Reference Range Information
Class
IgE kU/L
Interpretation
0
<0.35
Negative
1
0.35-0.69
Equivocal
2
0.70-3.49
Positive
3
3.50-17.4
Positive
4
17.5-49.9
Strongly positive
5
50.0-99.9
Strongly positive
6
> or =100
Strongly positive
Interpretation
Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
 
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories Monday through Saturday​ ​Same day/1 day Fluorescence Enzyme Immunoassay (FEIA)​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86008 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.