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25676 Allergen, Rabbit Epithelium, IgE (REPII)

Allergen, Rabbit Epithelium, IgE (REPII)
Test Code: ALRBESO
Synonyms/Keywords
​Common European Rabbit epithelium, Domestic Rabbit epithelium, European Rabbit epithelium, Oryctolagus cuniculus, Rabbit epithelium
Useful For
​Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
 
Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum ​Red Top Tube (RTT) ​Serum Separter Tube (SST) ​0.5 mL for each 5 allergens requested ​For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Refrigerated (preferred) ​14 days
​Frozen ​90 days
Interference
​Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context. 
 
False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2,500 kU/L) due to nonspecific binding to allergen solid phases.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Saturday ​Same day/1 day ​Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories
Class
IgE kU/L
Interpretation
0
<0.35
Negative
1
0.35-0.69
Equivocal
2
0.70-3.49
Positive
3
3.50-17.4
Positive
4
17.5-49.9
Strongly positive
5
50.0-99.9
Strongly positive
6
> or =100
Strongly positive
Reference values apply to all ages.
Interpretation
​Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
 
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86003​ ​ ​1 ​Allergen specific IgE quan/semiquan each allergen ​
Synonyms/Keywords
​Common European Rabbit epithelium, Domestic Rabbit epithelium, European Rabbit epithelium, Oryctolagus cuniculus, Rabbit epithelium
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum ​Red Top Tube (RTT) ​Serum Separter Tube (SST) ​0.5 mL for each 5 allergens requested ​For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Refrigerated (preferred) ​14 days
​Frozen ​90 days
Interference
​Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context. 
 
False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2,500 kU/L) due to nonspecific binding to allergen solid phases.
Useful For
​Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
 
Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories
Class
IgE kU/L
Interpretation
0
<0.35
Negative
1
0.35-0.69
Equivocal
2
0.70-3.49
Positive
3
3.50-17.4
Positive
4
17.5-49.9
Strongly positive
5
50.0-99.9
Strongly positive
6
> or =100
Strongly positive
Reference values apply to all ages.
Interpretation
​Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
 
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Saturday ​Same day/1 day ​Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86003​ ​ ​1 ​Allergen specific IgE quan/semiquan each allergen ​
For most current information refer to the Marshfield Laboratory online reference manual.