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26055 Granulocyte Antibodies, Serum (LAGGT)

Granulocyte Antibodies, Serum (LAGGT)
Test Code: LAGGTSO
Synonyms/Keywords
​​Anti-Leukocyte Antibodies
Anti-Neutrophil
Antigranulocyte Antibodies
Granulocyte Ab
Granulocyte Binding IgG
Leukoagglutinin
Neutrophil Antibodies
Anti-Leukocyte Ab
Useful For

The work-up of individuals having febrile, nonhemolytic transfusion reactions.

The detection of individuals with autoimmune neutropenia.

Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Red Top Tube ​1.5 mL ​0.3 mL
Collection Processing Instructions
Only pretransfusion reaction specimen is acceptable.
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​30 days
​Ambient ​7 days
​Frozen ​365 days
Rejection Criteria
Serum gel tube
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Tuesday, Wednesday, Friday ​9 days Purified granulocyte preparations from normal donors are incubated with patient's test serum and then with fluorescein-tagged antihuman globulin reagent. Sera containing the antibodies deposit immunoglobulin on the target cell membrane which is detected by the second stage antibody and visualized by fluorescence microscopy.
Reference Lab
Reference Range Information
See Report
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86021 ​1
Synonyms/Keywords
​​Anti-Leukocyte Antibodies
Anti-Neutrophil
Antigranulocyte Antibodies
Granulocyte Ab
Granulocyte Binding IgG
Leukoagglutinin
Neutrophil Antibodies
Anti-Leukocyte Ab
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Red Top Tube ​1.5 mL ​0.3 mL
Collection Processing
Only pretransfusion reaction specimen is acceptable.
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​30 days
​Ambient ​7 days
​Frozen ​365 days
Rejection Criteria
Serum gel tube
Useful For

The work-up of individuals having febrile, nonhemolytic transfusion reactions.

The detection of individuals with autoimmune neutropenia.

Reference Range Information
See Report
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Tuesday, Wednesday, Friday ​9 days Purified granulocyte preparations from normal donors are incubated with patient's test serum and then with fluorescein-tagged antihuman globulin reagent. Sera containing the antibodies deposit immunoglobulin on the target cell membrane which is detected by the second stage antibody and visualized by fluorescence microscopy.
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86021 ​1
For most current information refer to the Marshfield Laboratory online reference manual.