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22566 Dilute Russell Viper Venom Time

Dilute Russell Viper Venom Time
Test Code: DRVVT
Synonyms/Keywords
​DRVVT
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
*Platelet Poor Plasma 3.2% Citrated Blue Top Tube (BTT)​ ​ 0.75 mL ​ 0.75 mL ​ 0.5 mL​
Collection Processing Instructions

​One 0.75 mL citrated Blue Top Tube (BTT) plasma aliquot.
If more than one coagulation test is ordered, a separate aliquot is needed for each test.
-Collect in Citrated Blue Top Tube (BTT)
-Citrate anticoagulant must be adjusted for HCT >55%
-Tube must be at least 90% full
-Invert completely 3-4 times (without shaking) to mix
*See Instructions for: Preparation of Platelet Poor Plasma

Specimen Stability Information
Specimen Type Temperature Time
​Plasma ​Frozen ​6 months
Rejection Criteria
Clotted or Hemolyzed
​Contamination with IV or Hickman Line fluids
​Specimens that thaw during storage or transport
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield ​Monday, Wednesday, Friday Less than 2 hours​ Optical Clot Detection/Siemens BCSXP​
Test Information
To increase the sensitivity and specificity of the laboratory diagnosis of lupus anticoagulants (LA), both PTT-LA and DRVVT should be ordered.  These two tests have been combined as "Lupus Anticoagulant Panel (LAPAN)" for ordering convenience.
 
Lupus anticoagulant testing (DRVVT and PTT-LA) should not be performed on patients receiving rivaroxaban, apixaban, dabigatran, edoxaban, or warfarin.  For patients on these medications, one may consider anticardiolipin antibody and/or anti-beta-2 glycoprotein 1 antibody testing.
 
Reference Range Information
Performing Location Reference Range
​Marshfield
DRVVT: 29.2 - 37.8 seconds
If DRVVT is > 37.8 seconds, a DRVVPH is also performed and the ratio of DRVVT/DRVVPH is also reported
 
Ratio: 0.8 - 1.1
Ratio > 1.1: Positive for LA
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​85613 ​ ​ ​Optical Clot Detection ​
Synonyms/Keywords
​DRVVT
Ordering Applications
Ordering Application Description
​Centricity

​a. Dil-Russells Viper Venom Time 

b. Russells Viper Menom Dil

​Cerner ​Dilute Russell Viper Venom Time
​COM ​DRVVT-Dil-Russells Viper Venom
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
*Platelet Poor Plasma 3.2% Citrated Blue Top Tube (BTT)​ ​ 0.75 mL ​ 0.75 mL ​ 0.5 mL​
Collection Processing

​One 0.75 mL citrated Blue Top Tube (BTT) plasma aliquot.
If more than one coagulation test is ordered, a separate aliquot is needed for each test.
-Collect in Citrated Blue Top Tube (BTT)
-Citrate anticoagulant must be adjusted for HCT >55%
-Tube must be at least 90% full
-Invert completely 3-4 times (without shaking) to mix
*See Instructions for: Preparation of Platelet Poor Plasma

Specimen Stability Information
Specimen Type Temperature Time
​Plasma ​Frozen ​6 months
Rejection Criteria
Clotted or Hemolyzed
​Contamination with IV or Hickman Line fluids
​Specimens that thaw during storage or transport
Reference Range Information
Performing Location Reference Range
​Marshfield
DRVVT: 29.2 - 37.8 seconds
If DRVVT is > 37.8 seconds, a DRVVPH is also performed and the ratio of DRVVT/DRVVPH is also reported
 
Ratio: 0.8 - 1.1
Ratio > 1.1: Positive for LA
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield ​Monday, Wednesday, Friday Less than 2 hours​ Optical Clot Detection/Siemens BCSXP​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​85613 ​ ​ ​Optical Clot Detection ​
For most current information refer to the Marshfield Laboratory online reference manual.