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22615 Immunoglobulin D (IgD), Serum (IGD)

Immunoglobulin D (IgD), Serum (IGD)
Test Code:  IGDSO
Synonyms/Keywords
​Ref Lab Code: 9272, IgD (Immunoglobulin D), Immune Competence
Useful For
​Quantitative determination of the immunoglobulins can provide important information on the humoral immune status.
 
Changes in IgD concentration are used as a marker of changes in the size of the clone of monoclonal IgD plasma cells.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ Red Top Tube (RTT)​ Serum Separator Tube (SST)​ 1 mL​ 0.5 mL​ ​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerated (preferred)​ 21 days​
​ Ambient ​ 21 days​
​ Frozen ​ 21 days​
Rejection Criteria
Gross lipemia
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​
 Monday through Saturday​
Same day/1 day​
Nephelometry​
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
0-10 mg/dL
Interpretation
​The physiologic significance of serum IgD concentration is unclear and in many normal persons serum IgD is undetectable.
 
Increased concentrations may be due to polyclonal (reactive) or monoclonal plasma cell proliferative processes.
 
A monoclonal IgD protein is present in 1% of patients with myeloma. Monoclonal IgD proteins are often in low concentrations and do not have a quantifiable M-peak on serum protein electrophoresis. However, the presence of an IgD monoclonal protein is almost always indicative of a malignant plasma cell disorder such as multiple myeloma or primary amyloidosis.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​82784 ​ ​ ​ ​
Synonyms/Keywords
​Ref Lab Code: 9272, IgD (Immunoglobulin D), Immune Competence
Ordering Applications
Ordering Application Description
​Centricity ​IgD Quantitation
​Cerner IgD​
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ Red Top Tube (RTT)​ Serum Separator Tube (SST)​ 1 mL​ 0.5 mL​ ​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerated (preferred)​ 21 days​
​ Ambient ​ 21 days​
​ Frozen ​ 21 days​
Rejection Criteria
Gross lipemia
Useful For
​Quantitative determination of the immunoglobulins can provide important information on the humoral immune status.
 
Changes in IgD concentration are used as a marker of changes in the size of the clone of monoclonal IgD plasma cells.
Reference Range Information
0-10 mg/dL
Interpretation
​The physiologic significance of serum IgD concentration is unclear and in many normal persons serum IgD is undetectable.
 
Increased concentrations may be due to polyclonal (reactive) or monoclonal plasma cell proliferative processes.
 
A monoclonal IgD protein is present in 1% of patients with myeloma. Monoclonal IgD proteins are often in low concentrations and do not have a quantifiable M-peak on serum protein electrophoresis. However, the presence of an IgD monoclonal protein is almost always indicative of a malignant plasma cell disorder such as multiple myeloma or primary amyloidosis.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​
 Monday through Saturday​
Same day/1 day​
Nephelometry​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​82784 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.