Skip Ribbon Commands
Skip to main content
Sign In
Navigate Up

22635 Fluoxetine, Serum (FLUOX)

Fluoxetine, Serum (FLUOX)
Test Code: FLUOX
Synonyms/Keywords
Fluoxetine (Prozac), Norfluoxetine, Prozac (Fluoxetine Hydrochloride)
Useful For
​Monitoring serum concentration of fluoxetine during therapy
 
Evaluating potential toxicity
 
Evaluating patient compliance
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum Red Top Tube (RTT)​ ​ 1 mL​ 0.5 mL​ ​
Collection Processing Instructions
​Spin down and separate serum from cells within 2 hours of draw.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerated (preferred)​ 28 days​
​ Frozen ​ 28 days​
​ Room Temperature ​ 72 hours​
Rejection Criteria
​Serum gel tube
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​
 Tuesday
2 days
​
Liquid Chromatography Mass Spectrometry (LC-MS/MS)​
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Fluoxetine + norfluoxetine: 120-500 ng/mL
Interpretation
​Most individuals display optimal response to fluoxetine when combined serum levels of fluoxetine and norfluoxetine are between 120 and 300 ng/mL. Some individuals may respond well outside of this range, or may display toxicity within the therapeutic range, thus interpretation should include clinical evaluation. A toxic range has not been well established.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​80299 ​ ​ ​ ​
Synonyms/Keywords
Fluoxetine (Prozac), Norfluoxetine, Prozac (Fluoxetine Hydrochloride)
Ordering Applications
Ordering Application Description
​Centricity ​Fluoxetine (Prozac)
​Cerner ​Fluoxetine Level (80228)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum Red Top Tube (RTT)​ ​ 1 mL​ 0.5 mL​ ​
Collection Processing
​Spin down and separate serum from cells within 2 hours of draw.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerated (preferred)​ 28 days​
​ Frozen ​ 28 days​
​ Room Temperature ​ 72 hours​
Rejection Criteria
​Serum gel tube
Useful For
​Monitoring serum concentration of fluoxetine during therapy
 
Evaluating potential toxicity
 
Evaluating patient compliance
Reference Range Information
Fluoxetine + norfluoxetine: 120-500 ng/mL
Interpretation
​Most individuals display optimal response to fluoxetine when combined serum levels of fluoxetine and norfluoxetine are between 120 and 300 ng/mL. Some individuals may respond well outside of this range, or may display toxicity within the therapeutic range, thus interpretation should include clinical evaluation. A toxic range has not been well established.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​
 Tuesday
2 days
​
Liquid Chromatography Mass Spectrometry (LC-MS/MS)​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​80299 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.