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22675 Granulocyte Antibodies (LAGGT)

Granulocyte Antibodies (LAGGT)
Test Code: MISC
Synonyms/Keywords
Ref Lab Code: 8976, Anti-Leukocyte Antibodies, Anti-Neutrophil, Antigranulocyte Antibodies, Granulocyte Ab,
Granulocyte Binding IgG, Leukoagglutinin, Neutrophil Antibodies, Anti-Leukocyte Ab 
Useful For
​The work-up of individuals having febrile, nonhemolytic transfusion reactions
 
The detection of individuals with autoimmune neutropenia
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum Red Top Tube (RTT)​ ​ 1.5 mL​ 0.3 mL​ ​
Collection Processing Instructions
​Only pretransfusion reaction specimen is acceptable.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerated (preferred)​ 30 days​
​ Frozen ​ 365 days​
​ Ambient ​ 7 days​
Rejection Criteria
Serum gel tubes
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​
 Monday, Wednesday, Friday​
7 days​
Indirect Immunofluorescence​
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Negative. Reported as positive or negative.
Interpretation
​A positive result in an individual being worked up for a febrile transfusion reaction indicates the need for leukocyte-poor (filtered) red blood cells.
 
This test cannot distinguish between allo- and autoantibodies
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86021 ​ ​ ​ ​
Synonyms/Keywords
Ref Lab Code: 8976, Anti-Leukocyte Antibodies, Anti-Neutrophil, Antigranulocyte Antibodies, Granulocyte Ab,
Granulocyte Binding IgG, Leukoagglutinin, Neutrophil Antibodies, Anti-Leukocyte Ab 
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum Red Top Tube (RTT)​ ​ 1.5 mL​ 0.3 mL​ ​
Collection Processing
​Only pretransfusion reaction specimen is acceptable.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerated (preferred)​ 30 days​
​ Frozen ​ 365 days​
​ Ambient ​ 7 days​
Rejection Criteria
Serum gel tubes
Useful For
​The work-up of individuals having febrile, nonhemolytic transfusion reactions
 
The detection of individuals with autoimmune neutropenia
Reference Range Information
Negative. Reported as positive or negative.
Interpretation
​A positive result in an individual being worked up for a febrile transfusion reaction indicates the need for leukocyte-poor (filtered) red blood cells.
 
This test cannot distinguish between allo- and autoantibodies
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​
 Monday, Wednesday, Friday​
7 days​
Indirect Immunofluorescence​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86021 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.