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22784 Platelet Aggregation

Platelet Aggregation
Test Code: PLTAGG
Test Components
Agonsists tested:  Epinephrine, ADP, Ristocetin, Collagen and Arachidonic Acid​
Useful For
​Unless the provider is looking for evidence of drug efficacy (e.g. clopidogrel or aspirin resistance), it is strongly recommended that patients discontinue all medications that may inhibit platelet function.  These would include aspirin (discontinue for 7 days prior to testing) and nonsteriodal anti-inflammatory drugs (NSAIDs) such ibuprofen, naproxen, etc (discontinue for 3 days prior to testing).  There is also a long list of drugs which are purported to affect platelet aggregation, but the documention in the medical literature is scant and/or inconsistent.  Please contact a hemotopathologist with pre-analytical questions for platelet aggregation testing:  Gene R. Shaw, MD or Kajal V. Sitwala, MD.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Recommended - 12 hours Citrated Plasma​ Special Collection Tubes Provided by Clinical Manual ​ Two Special Collection Tubes​ One Special Collection Tube​ ​One Special Collection Tube
Collection Processing Instructions

Testing must be scheduled with Lab-Clinical Microscopic section.

Only drawn at the Marshfield Main Campus, Monday through Friday 0800-1500. Samples drawn after 1500 will not be accepted. Call 715-221-6383 prior to ordering test. Clinical Microscopic provides the collection tubes.

Specimen must be hand-carried to the lab and walked over to the Clinical Microscopic section.

Specimen Stability Information
Specimen Type Temperature Time
​Citrated Whole Blood Ambient ​3 hours
Rejection Criteria
Lipemic samples
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield ​Monday through Friday ​1 day ​Bio/Data PAP- 8E Platelet Aggregometer
Reference Range Information
Performing Location Reference Range
​Marshfield ​Interpretive Report
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​85576 ​ 5​ ​ ​
Test Components
Agonsists tested:  Epinephrine, ADP, Ristocetin, Collagen and Arachidonic Acid​
Ordering Applications
Ordering Application Description
​Centricity ​Platelet Aggregation
​Cerner ​Platelet Aggregation
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Recommended - 12 hours Citrated Plasma​ Special Collection Tubes Provided by Clinical Manual ​ Two Special Collection Tubes​ One Special Collection Tube​ ​One Special Collection Tube
Collection Processing

Testing must be scheduled with Lab-Clinical Microscopic section.

Only drawn at the Marshfield Main Campus, Monday through Friday 0800-1500. Samples drawn after 1500 will not be accepted. Call 715-221-6383 prior to ordering test. Clinical Microscopic provides the collection tubes.

Specimen must be hand-carried to the lab and walked over to the Clinical Microscopic section.

Specimen Stability Information
Specimen Type Temperature Time
​Citrated Whole Blood Ambient ​3 hours
Rejection Criteria
Lipemic samples
Useful For
​Unless the provider is looking for evidence of drug efficacy (e.g. clopidogrel or aspirin resistance), it is strongly recommended that patients discontinue all medications that may inhibit platelet function.  These would include aspirin (discontinue for 7 days prior to testing) and nonsteriodal anti-inflammatory drugs (NSAIDs) such ibuprofen, naproxen, etc (discontinue for 3 days prior to testing).  There is also a long list of drugs which are purported to affect platelet aggregation, but the documention in the medical literature is scant and/or inconsistent.  Please contact a hemotopathologist with pre-analytical questions for platelet aggregation testing:  Gene R. Shaw, MD or Kajal V. Sitwala, MD.
Test Components
Agonsists tested:  Epinephrine, ADP, Ristocetin, Collagen and Arachidonic Acid​
Reference Range Information
Performing Location Reference Range
​Marshfield ​Interpretive Report
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield ​Monday through Friday ​1 day ​Bio/Data PAP- 8E Platelet Aggregometer
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​85576 ​ 5​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.