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22986 Protein S Antigen, On Coumadin (300059)

Protein S Antigen, On Coumadin (300059)
Test Code: PROT-SM
Synonyms/Keywords
​Protein S Antigen, Protein S Antigen/Factor VII Antigen Ratio
Test Components
​Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Platelet poor plasma​ ​Citrated Blue Top Tube (BTT) ​ ​1 mL ​0.5 mL ​
Collection Processing Instructions

​For this test, patients must be on a stable dose of Coumadin for at least two weeks. If patient has not received Coumadin for the past two weeks, see 'Protein S Antigen, No Coumadin'.

One 1.0 mL aliquot of platelet-poor plasma (BTT). This tube must be drawn at least 90% full. Invert tubes completely three or four times to mix. Do Not Shake. Centrifuge tube at 3000 rpm for 10 minutes with the brake OFF. Transfer plasma to polypropylene tubes with plastic pipettes. Cap tightly.

Specimen Stability Information
Specimen Type Temperature Time
​Plasma

Freeze at -70 deg C.

(preferable at -70 deg C, but -20 deg C is acceptable for outreach).​

 8 weeks​
Rejection Criteria

Specimens in glass tubes, non-platelet poor, hemolyzed, grossly lipemic or thawed specimens are

unacceptable

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Esoterix Coagulation Laboratory​ Monday and Thursday​ ​2-4 days ​ELISA
Reference Lab
Esoterix Coagulation Laboratory
Test Information
​Factor VII Ag is a research use only test, not for use in diagnostic procedures.
Reference Range Information
Performing Location Reference Range
​Esoterix Coagulation Laboratory Indicated on report​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​85305 ​ ​1 ​Protein S, total ​
Synonyms/Keywords
​Protein S Antigen, Protein S Antigen/Factor VII Antigen Ratio
Test Components
​Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Ordering Applications
Ordering Application Description
​Centricity ​Protein S Antigen-On Coumadin
​Cerner ​Protein S Antigen-ON Coumadin
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Platelet poor plasma​ ​Citrated Blue Top Tube (BTT) ​ ​1 mL ​0.5 mL ​
Collection Processing

​For this test, patients must be on a stable dose of Coumadin for at least two weeks. If patient has not received Coumadin for the past two weeks, see 'Protein S Antigen, No Coumadin'.

One 1.0 mL aliquot of platelet-poor plasma (BTT). This tube must be drawn at least 90% full. Invert tubes completely three or four times to mix. Do Not Shake. Centrifuge tube at 3000 rpm for 10 minutes with the brake OFF. Transfer plasma to polypropylene tubes with plastic pipettes. Cap tightly.

Specimen Stability Information
Specimen Type Temperature Time
​Plasma

Freeze at -70 deg C.

(preferable at -70 deg C, but -20 deg C is acceptable for outreach).​

 8 weeks​
Rejection Criteria

Specimens in glass tubes, non-platelet poor, hemolyzed, grossly lipemic or thawed specimens are

unacceptable

Test Components
​Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Reference Range Information
Performing Location Reference Range
​Esoterix Coagulation Laboratory Indicated on report​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Esoterix Coagulation Laboratory​ Monday and Thursday​ ​2-4 days ​ELISA
Reference Lab
Esoterix Coagulation Laboratory
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​85305 ​ ​1 ​Protein S, total ​
For most current information refer to the Marshfield Laboratory online reference manual.