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23117 Porphobilinogen Quant, Random Urine (PBGU)

Porphobilinogen Quant, Random Urine (PBGU)
Test Code: MISC
Synonyms/Keywords
​Ref Lab Code: 82068,
Acute Intermittent Porphyria (AIP), AIP (Acute Intermittent Porphyria), HCP (Hereditary Coproporphyria), Hereditary Coproporphyria (HCP), PBG (Porphobilinogen), Porphobilinogen (PBG)Variegate Porphyria (VP), VP (Variegate Porphyria)
Useful For
​First-line test for establishing a tentative diagnosis for acute neuropathic porphyria including acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Urine Amber, 60-mL urine bottle​ ​ 20 mL​ 15 mL​ ​
Collection Processing Instructions
​1. Collect a random urine specimen.
2. No preservative necessary but pH must be >5.0.
3. Protect specimen from light.
Specimen Stability Information
Specimen Type Temperature Time
Urine​ Frozen (preferred)​ 7 days​
​ Refrigerated ​ 7 days​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories Monday through Friday​ 2 days(not reported on Saturday or Sunday)​
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis​
Reference Lab
Mayo Clinic Laboratories
Test Information
Test is useful as a first-line test for establishing a tentative diagnosis for acute neuropathic porphyria including AIP, HCP and VP.​
Reference Range Information
<= 1.3 mcmol/L
Interpretation
​Abnormal results are reported with a detailed interpretation including an overview of the results and their significance, a correlation to available clinical information provided with the specimen, differential diagnosis, and recommendations for additional testing when indicated and available, and a phone number to reach one of the laboratory directors in case the referring physician has additional questions.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​84110 ​ ​ ​ ​
Synonyms/Keywords
​Ref Lab Code: 82068,
Acute Intermittent Porphyria (AIP), AIP (Acute Intermittent Porphyria), HCP (Hereditary Coproporphyria), Hereditary Coproporphyria (HCP), PBG (Porphobilinogen), Porphobilinogen (PBG)Variegate Porphyria (VP), VP (Variegate Porphyria)
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Urine Amber, 60-mL urine bottle​ ​ 20 mL​ 15 mL​ ​
Collection Processing
​1. Collect a random urine specimen.
2. No preservative necessary but pH must be >5.0.
3. Protect specimen from light.
Specimen Stability Information
Specimen Type Temperature Time
Urine​ Frozen (preferred)​ 7 days​
​ Refrigerated ​ 7 days​
Useful For
​First-line test for establishing a tentative diagnosis for acute neuropathic porphyria including acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria.
Reference Range Information
<= 1.3 mcmol/L
Interpretation
​Abnormal results are reported with a detailed interpretation including an overview of the results and their significance, a correlation to available clinical information provided with the specimen, differential diagnosis, and recommendations for additional testing when indicated and available, and a phone number to reach one of the laboratory directors in case the referring physician has additional questions.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories Monday through Friday​ 2 days(not reported on Saturday or Sunday)​
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​84110 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.