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23158 Thiopurine Metabolites, Prometheus (3200)

Thiopurine Metabolites, Prometheus (3200)
Test Code: PROPDSO
Synonyms/Keywords
 Imuran, 6MP
Useful For
​This test is used during treatment for the on-going evaluation of patient response to AZA/6-MP therapy. It helps optimize ongoing dosing of thiopurine immunosuppressant therapy to reach and maintain therapeutic goal. Thiopurine metabolite testing also helps to identify drug metabolite levels that may lead to toxicity and some of the reasons for treatment failure.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Whole Blood ​EDTA Lavender Top Tube (LTT) ​ ​5 ml ​2.5 mL ​
Collection Processing Instructions
​Indicate current therapeutic dosage for drug tested (6MP or Azothioprine)
Specimen Stability Information
Specimen Type Temperature Time
​Whole Blood ​ ​Ambient ​24 hours
​Refrigerated ​8 days
Rejection Criteria
Samples other than EDTA Reject
​Frozen ​Reject
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​3 days ​HPLC
Reference Lab
Prometheus Biosciences
Reference Range Information
Performing Location Reference Range
Prometheus Labs​ ​Interpretive Report
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
82542 ​ ​2 ​
Synonyms/Keywords
 Imuran, 6MP
Ordering Applications
Ordering Application Description
​Centricity ​Pro-Predict R-6MP/AZ
​Cerner ​Thiopurine Metabolites, Prometheus (3200)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Whole Blood ​EDTA Lavender Top Tube (LTT) ​ ​5 ml ​2.5 mL ​
Collection Processing
​Indicate current therapeutic dosage for drug tested (6MP or Azothioprine)
Specimen Stability Information
Specimen Type Temperature Time
​Whole Blood ​ ​Ambient ​24 hours
​Refrigerated ​8 days
Rejection Criteria
Samples other than EDTA Reject
​Frozen ​Reject
Useful For
​This test is used during treatment for the on-going evaluation of patient response to AZA/6-MP therapy. It helps optimize ongoing dosing of thiopurine immunosuppressant therapy to reach and maintain therapeutic goal. Thiopurine metabolite testing also helps to identify drug metabolite levels that may lead to toxicity and some of the reasons for treatment failure.
Reference Range Information
Performing Location Reference Range
Prometheus Labs​ ​Interpretive Report
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​3 days ​HPLC
Reference Lab
Prometheus Biosciences
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
82542 ​ ​2 ​
For most current information refer to the Marshfield Laboratory online reference manual.