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Lab Test Reference Manual
Human Reference Manual
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23233
Lab Test Reference Manual
Human Reference Manual
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23233
Tissue Transglutaminase AB, IgA and IgG
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Marshfield Clinic Public WebSite
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Site Contents
Tissue Transglutaminase AB, IgA and IgG
Test Code: TTGAB
Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding
Synonyms/Keywords
Synonyms, Keywords
tTG Ab, celiac disease, sprue
Useful For
Useful For
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten-sensitive enteropathy (Celiac disease). The tTG-IgG assay may aid in the diagnosis of gluten sensitive enteropathy in tTG-IgA negative patients with confirmed IgA deficiency. A negative Tissue Transglutaminase antibody test alone does not rule out gluten-sensitive enteropathy.
Specimen Requirements
Specimen Requirements
Fasting Required
Specimen Type
Preferred Container/Tube
Acceptable Container/Tube
Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No
Serum
Red Top Tube (RTT) or Serum Separator Tube (SST)
1.0 mL
1.0 mL
0.5 mL
Specimen Stability Information
Specimen Stability Information
Specimen Type
Temperature
Time
Serum
Refrigerate
7 days
Frozen
> 7 days
Rejection Criteria
Rejection Criteria
Gross lipemia
Gross hemolysis
Heat inactivated samples
Performing Laboratory Information
Performing Laboratory Information
Performing Location
Day(s) Test Performed
Analytical Time
Methodology/Instrumentation
Marshfield
Monday, Wednesday, Friday
1 day
Enzyme Immunoassay (EIA)
Reference Range Information
Reference Range Information
Performing Location
Reference Range
Marshfield
IgG:
< 6.0 U/mL: Negative
6.0 - 9.0 U/mL: Weak Positive
> 9.0 U/mL: Positive
IgA:
< 4.0 U/mL: Negative
4.0-10.0 U/mL: Weak Positive
> 10.0 U/mL: Positive
Outreach CPTs
Outreach CPT Codes
CPT
Modifier
(if needed)
Quantity
Description
Comments
83516
2
tTG IgG and tTG IgA
Synonyms/Keywords
Synonyms, Keywords
tTG Ab, celiac disease, sprue
Ordering Applications
Ordering Applications
Ordering Application
Description
Centricity
Tissue Transglut IgA & IgG
Cerner
Tissue Transglutaminase Antibody IgA and IgG
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Requirements
Fasting Required
Specimen Type
Preferred Container/Tube
Acceptable Container/Tube
Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No
Serum
Red Top Tube (RTT) or Serum Separator Tube (SST)
1.0 mL
1.0 mL
0.5 mL
Specimen Stability Information
Specimen Stability Information
Specimen Type
Temperature
Time
Serum
Refrigerate
7 days
Frozen
> 7 days
Rejection Criteria
Rejection Criteria
Gross lipemia
Gross hemolysis
Heat inactivated samples
Useful For
Useful For
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten-sensitive enteropathy (Celiac disease). The tTG-IgG assay may aid in the diagnosis of gluten sensitive enteropathy in tTG-IgA negative patients with confirmed IgA deficiency. A negative Tissue Transglutaminase antibody test alone does not rule out gluten-sensitive enteropathy.
Reference Range Information
Reference Range Information
Performing Location
Reference Range
Marshfield
IgG:
< 6.0 U/mL: Negative
6.0 - 9.0 U/mL: Weak Positive
> 9.0 U/mL: Positive
IgA:
< 4.0 U/mL: Negative
4.0-10.0 U/mL: Weak Positive
> 10.0 U/mL: Positive
For more information visit:
http://labtestsonline.org
Performing Laboratory Information
Performing Laboratory Information
Performing Location
Day(s) Test Performed
Analytical Time
Methodology/Instrumentation
Marshfield
Monday, Wednesday, Friday
1 day
Enzyme Immunoassay (EIA)
For billing questions, see Contacts
Outreach CPTs
Outreach CPT Codes
CPT
Modifier
(if needed)
Quantity
Description
Comments
83516
2
tTG IgG and tTG IgA
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For most current information refer to the Marshfield Laboratory online reference manual.