Positive IgM results are consistent with acute infection, although false positives do occur (see Cautions).
A single positive IgG result only indicates previous immunologic exposure.
Negative results do not rule-out the presence of Mycoplasma pneumoniae-associated disease. The specimen may have been drawn before the appearance of detectable antibodies. If testing is performed too early following primary infection, IgG and/or IgM may not be detectable. If a Mycoplasma infection is clinically indicated, a second specimen should be submitted at least 14 days later.