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25063 Natural Killer (CD16, CD56, CD57) Profile

Natural Killer (CD16, CD56, CD57) Profile
Test Code: NK
Synonyms/Keywords
Flow Cytometry​
Useful For
Changes in the NK profile may be useful to monitor the response to therapy in Lyme disease.​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Whole blood​ Sodium-heparin Green Top Tube (GTT)​ ​** EDTA 1.0 mL​ 1.0 mL​ 0.5 mL​
Collection Processing Instructions
Not to be ordered by Marshfield Clinic, Regional Centers, or Marshfield Medical Center. 
Must be ordered as a 63 accession for Outreach facilities only.
 
If a CBC with differential has been performed within 4 hours of the collection for the NK Profile, please send a copy of the CBC with differential results along with the NK Profile specimen. If a CBC with differential has not been performed in this time period, include an order for the CBC with differential. This requires a separate EDTA whole blood (LTT) and two unstained EDTA smears. Notify Flow Cytometry Lab (800-222-5835, ext. 16385) before sending the specimen.
 
Specimen must arrive in Flow Cytometry within 48 hours of collection. ​
 
** For EDTA specimens, please call 800-222-5835, ext. 16385 to determine acceptability.
Specimen Stability Information
Specimen Type Temperature Time
Whole blood​ Room temperature​ 72 hours​
Rejection Criteria
Fixed specimens
Specimens greater than 72 hours old ​
Refrigerated or frozen specimens​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Flow Cytometry​
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the U.S. Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical testing.
 
Absolute counts for this test are based on the CBC results provided at the time of testing, including lymphocyte percentage.
​
Reference Range Information
Performing Location Reference Range
Marshfield​ Not applicable
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
88184​ ​ ​1 ​Flow Cytometry, first marker ​
​88185 ​ ​3 ​Additional marker, each ​
​
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the U.S. Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical testing.
Synonyms/Keywords
Flow Cytometry​
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Whole blood​ Sodium-heparin Green Top Tube (GTT)​ ​** EDTA 1.0 mL​ 1.0 mL​ 0.5 mL​
Collection Processing
Not to be ordered by Marshfield Clinic, Regional Centers, or Marshfield Medical Center. 
Must be ordered as a 63 accession for Outreach facilities only.
 
If a CBC with differential has been performed within 4 hours of the collection for the NK Profile, please send a copy of the CBC with differential results along with the NK Profile specimen. If a CBC with differential has not been performed in this time period, include an order for the CBC with differential. This requires a separate EDTA whole blood (LTT) and two unstained EDTA smears. Notify Flow Cytometry Lab (800-222-5835, ext. 16385) before sending the specimen.
 
Specimen must arrive in Flow Cytometry within 48 hours of collection. ​
 
** For EDTA specimens, please call 800-222-5835, ext. 16385 to determine acceptability.
Specimen Stability Information
Specimen Type Temperature Time
Whole blood​ Room temperature​ 72 hours​
Rejection Criteria
Fixed specimens
Specimens greater than 72 hours old ​
Refrigerated or frozen specimens​
Useful For
Changes in the NK profile may be useful to monitor the response to therapy in Lyme disease.​
Reference Range Information
Performing Location Reference Range
Marshfield​ Not applicable
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Flow Cytometry​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
88184​ ​ ​1 ​Flow Cytometry, first marker ​
​88185 ​ ​3 ​Additional marker, each ​
​
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the U.S. Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical testing.
For most current information refer to the Marshfield Laboratory online reference manual.