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25126 Beta 2 Glycoprotein 1 Antibody Screen

Beta 2 Glycoprotein 1 Antibody Screen
Test Code: B2GSCRN
Synonyms/Keywords
B2GP1, Beta 2 Glycoprotein Antibody, B2GP1 IgG, IgA, IgM​, B2IGA, B2IGG, B2IGM
Useful For

The Beta 2 Glycoprotein 1 antibody screen is useful to identify elevated levels of antibodies to phospholipid-protein complexes. Elevated levels of these antibodies are a diagnostic feature of the anti-phospholipid syndrome. The anti-phospholipid syndrome is an autoimmune disorder with significant obstetrical and vascular complications.​ 

NOTE - This test is used to screen for IgG, IgA or IgM antibodies to Beta 2 Glycoprotein 1. If the B2GSCRN is positive, a Beta-2-Glycoprotein 1 IgA (B2IGA), Beta-2-Glycoprotein 1 IgG (B2IGG) and a Beta-2-Glycoprotein 1 IgM (B2IGM) will be performed. For specific testing only, contact Clinic Esoteric Automated section at 715-221-6290.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST) ​ ​ 1.0 mL​ 0.5 mL​ 0.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​ 2 days​
Frozen > 2 days​
Rejection Criteria
Gross lipemia
Gross hemolysis​
Heat inactivated samples​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday-Wednesday-Friday​ 1 day​ Enzyme Immunoassay (EIA)​
Test Information
This test screens for IgG, IgM and IgA antibodies to Beta 2 Glycoprotein 1. If the screen is positive, separate determinations for Beta 2 Glycoprotein 1 IgG, IgM and IgA antibodies will be performed.​
Reference Range Information
Performing Location Reference Range
Marshfield​
B2Gp1 Screen: < 1.0 Negative
B2GP1 IgG:
  Normal = < 9.4 - 20.0 U/mL
  Positive = > 20.0 U/mL 
B2GP1 IgM:
  Normal = < 9.4 - 20.0 U/mL
  Positive = > 20.0 U/mL 
B2GP1 IgA:
  Normal = < 9.4 - 20.0 U/mL
  Positive = > 20.0 U/mL ​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86146​ ​ 1​ B2GP1 Screen​ ​
86146​ ​ 3​ B2GP1 IgG, IgA, IgM (as needed)  ​ ​
Synonyms/Keywords
B2GP1, Beta 2 Glycoprotein Antibody, B2GP1 IgG, IgA, IgM​, B2IGA, B2IGG, B2IGM
Ordering Applications
Ordering Application Description
​Centricity ​Beta2 Glycoprotein 1 Antibody Screen
​Cerner None​
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST) ​ ​ 1.0 mL​ 0.5 mL​ 0.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​ 2 days​
Frozen > 2 days​
Rejection Criteria
Gross lipemia
Gross hemolysis​
Heat inactivated samples​
Useful For

The Beta 2 Glycoprotein 1 antibody screen is useful to identify elevated levels of antibodies to phospholipid-protein complexes. Elevated levels of these antibodies are a diagnostic feature of the anti-phospholipid syndrome. The anti-phospholipid syndrome is an autoimmune disorder with significant obstetrical and vascular complications.​ 

NOTE - This test is used to screen for IgG, IgA or IgM antibodies to Beta 2 Glycoprotein 1. If the B2GSCRN is positive, a Beta-2-Glycoprotein 1 IgA (B2IGA), Beta-2-Glycoprotein 1 IgG (B2IGG) and a Beta-2-Glycoprotein 1 IgM (B2IGM) will be performed. For specific testing only, contact Clinic Esoteric Automated section at 715-221-6290.
Reference Range Information
Performing Location Reference Range
Marshfield​
B2Gp1 Screen: < 1.0 Negative
B2GP1 IgG:
  Normal = < 9.4 - 20.0 U/mL
  Positive = > 20.0 U/mL 
B2GP1 IgM:
  Normal = < 9.4 - 20.0 U/mL
  Positive = > 20.0 U/mL 
B2GP1 IgA:
  Normal = < 9.4 - 20.0 U/mL
  Positive = > 20.0 U/mL ​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday-Wednesday-Friday​ 1 day​ Enzyme Immunoassay (EIA)​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86146​ ​ 1​ B2GP1 Screen​ ​
86146​ ​ 3​ B2GP1 IgG, IgA, IgM (as needed)  ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.