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25149 Rufinamide, Serum (RUFI)

Rufinamide, Serum (RUFI)
Test Code: RUFINSO
Synonyms/Keywords
Banzel​
Useful For
Monitoring serum rufinamide concentrations, assessing compliance, and adjusting dosage in patients receiving other drugs which interact pharmacokinetically with rufinamide (ie, drugs that induce liver CYP3A4 enzymes) and may be helpful in who are receiving hemodialysis.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​1 mL ​0.5 mL ​
Collection Processing Instructions

1. Draw blood immediately before next scheduled dose.

2. For sustained-release formulations ONLY, draw blood a minimum of 12 hours after last dose.

3. Spin down within 2 hours of draw.

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​
Ambient 
 ​28 days
Refrigerate (preferred) 28 days
​Frozen ​28 days
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​ Tuesday, Thursday, Saturday; 2pm​ 1 day
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)​
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing Location Reference Range
Mayo Medical Laboratories​ 5.0-30.0 mcg/mL
Interpretation
​​The reference interval is broad and represents the concentrations observed to be associated with the greatest drug efficacy without side effects or toxicity.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
80299 ​ ​ ​ ​
Synonyms/Keywords
Banzel​
Ordering Applications
Ordering Application Description
Centricity​ Rufinamide, Serum (445)
​Cerner ​None
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​1 mL ​0.5 mL ​
Collection Processing

1. Draw blood immediately before next scheduled dose.

2. For sustained-release formulations ONLY, draw blood a minimum of 12 hours after last dose.

3. Spin down within 2 hours of draw.

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​
Ambient 
 ​28 days
Refrigerate (preferred) 28 days
​Frozen ​28 days
Useful For
Monitoring serum rufinamide concentrations, assessing compliance, and adjusting dosage in patients receiving other drugs which interact pharmacokinetically with rufinamide (ie, drugs that induce liver CYP3A4 enzymes) and may be helpful in who are receiving hemodialysis.
Reference Range Information
Performing Location Reference Range
Mayo Medical Laboratories​ 5.0-30.0 mcg/mL
Interpretation
​​The reference interval is broad and represents the concentrations observed to be associated with the greatest drug efficacy without side effects or toxicity.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​ Tuesday, Thursday, Saturday; 2pm​ 1 day
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
80299 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.