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25422 EGFR Gene Mutation, Tumor (EGFR)

EGFR Gene Mutation, Tumor (EGFR)
Test Code: EGF29SO
Synonyms/Keywords
Epidermal growth factor receptor, Non-small cell lung cancer, NSCLC, EGFR-tyrosine kinase inhibitor
Useful For
Identifying non-small cell lung cancers that may respond to epidermal growth factor receptor-tyrosine kinase inhibitor therapies.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)​​
No​ ​Tissue ​Formalin-fixed paraffin-embedded tissue block ​2 stained and 10 unstained slides ​ ​ ​
Collection Processing Instructions
Pathology report must accompany specimen in order for testing to be performed. Formalin-fixed, paraffin-embedded tissue block preferred or 1 slide stained with hematoxylin-and-eosin and 5 unstained, nonbaked slides with 5-microns thick sections of the tumor tissue is an acceptable minimum submission.  Mayo test code SLRVW - Slide Review is always performed at an added cost. 
Specimen Stability Information
Specimen Type ​​Temperature
Paraffin block ​Room Temperature ​
​Slides
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentatio​​n
​Sent to Mayo Medical Laboratories ​Monday through Friday ​5 days for EGFR only ​Scorpions real-time PCR and allele-specific PCR technologies
Reference Lab
Mayo Clinic Laboratories
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Commen​​ts
81235​ ​ ​1 ​ ​
​88381 ​ ​1 ​ ​
Synonyms/Keywords
Epidermal growth factor receptor, Non-small cell lung cancer, NSCLC, EGFR-tyrosine kinase inhibitor
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)​​
No​ ​Tissue ​Formalin-fixed paraffin-embedded tissue block ​2 stained and 10 unstained slides ​ ​ ​
Collection Processing
Pathology report must accompany specimen in order for testing to be performed. Formalin-fixed, paraffin-embedded tissue block preferred or 1 slide stained with hematoxylin-and-eosin and 5 unstained, nonbaked slides with 5-microns thick sections of the tumor tissue is an acceptable minimum submission.  Mayo test code SLRVW - Slide Review is always performed at an added cost. 
Specimen Stability Information
Specimen Type ​​Temperature
Paraffin block ​Room Temperature ​
​Slides
Useful For
Identifying non-small cell lung cancers that may respond to epidermal growth factor receptor-tyrosine kinase inhibitor therapies.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentatio​​n
​Sent to Mayo Medical Laboratories ​Monday through Friday ​5 days for EGFR only ​Scorpions real-time PCR and allele-specific PCR technologies
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Commen​​ts
81235​ ​ ​1 ​ ​
​88381 ​ ​1 ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.