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25625 T-Cell Receptor Gene Rearrange, PCR, Bld (TCGR)

T-Cell Receptor Gene Rearrange, PCR, Bld (TCGR)
Test Code: TCGRSO
Synonyms/Keywords
​Lymphoma vs Benign Process, Reactive Lymphocytic Process, T-Cell Gene Rearrangement, T Cell Gene Rearrangement
Useful For
​Determining whether a T-cell population is polyclonal or monoclonal
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Whole Blood ​EDTA Lavender Top Tube (LTT) ​ACD Yellow Top Tube (YTT) ​4 mL ​1 mL ​
Collection Processing Instructions

​Specimen must arrive within 168 hours of draw.

Include relevant clinical information and cytogenetics results, if available.

Include Hematopathology Patient Information Sheet.
(http://www.mayomedicallaboratories.com/it-mmfiles/hematopathology-request-form.pdf) 

Specimen Stability Information
Specimen Type Temperature Time
​Whole Blood ​ ​Room Temperature (preferred) ​7 days
​Refrigerate ​7 days
Rejection Criteria
Gross Hemolysis
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Friday ​5-10 days ​DNA Extracted for Analysis/Polymerase Chain Reaction (PCR)
Reference Lab
Mayo Clinic Laboratories
Test Information

This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the U.S. Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical testing.

​
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories ​​Positive, negative, or indeterminate for a clonal T-cell population
Interpretation
​An interpretive report will be provided. Results will be characterized as positive, negative, or indeterminate for a clonal T-cell population. In the appropriate clinicopathologic setting, a monoclonal result is associated with a neoplastic proliferation of T cells (see Cautions).
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​81340 ​ ​ ​TCB gene rearrangement, PCR ​
​81342 ​ ​ ​TCG @ gene rearrangement analysis ​
Classification

This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the U.S. Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical testing.

​
Synonyms/Keywords
​Lymphoma vs Benign Process, Reactive Lymphocytic Process, T-Cell Gene Rearrangement, T Cell Gene Rearrangement
Ordering Applications
Ordering Application Description
​COM ​T-Cell Receptor Rearrange PCR
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Whole Blood ​EDTA Lavender Top Tube (LTT) ​ACD Yellow Top Tube (YTT) ​4 mL ​1 mL ​
Collection Processing

​Specimen must arrive within 168 hours of draw.

Include relevant clinical information and cytogenetics results, if available.

Include Hematopathology Patient Information Sheet.
(http://www.mayomedicallaboratories.com/it-mmfiles/hematopathology-request-form.pdf) 

Specimen Stability Information
Specimen Type Temperature Time
​Whole Blood ​ ​Room Temperature (preferred) ​7 days
​Refrigerate ​7 days
Rejection Criteria
Gross Hemolysis
Useful For
​Determining whether a T-cell population is polyclonal or monoclonal
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories ​​Positive, negative, or indeterminate for a clonal T-cell population
Interpretation
​An interpretive report will be provided. Results will be characterized as positive, negative, or indeterminate for a clonal T-cell population. In the appropriate clinicopathologic setting, a monoclonal result is associated with a neoplastic proliferation of T cells (see Cautions).
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Friday ​5-10 days ​DNA Extracted for Analysis/Polymerase Chain Reaction (PCR)
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​81340 ​ ​ ​TCB gene rearrangement, PCR ​
​81342 ​ ​ ​TCG @ gene rearrangement analysis ​
Classification

This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the U.S. Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical testing.

​
For most current information refer to the Marshfield Laboratory online reference manual.