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25681 Immunoglobulin Subclass IgG4, Serum (IGGS4)

Immunoglobulin Subclass IgG4, Serum (IGGS4)
Test Code: IGGS4SO
Useful For
Supporting the diagnosis of IgG4-related disease
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​1 mL ​0.5 mL ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​14 days
​Ambient ​14 days
​Frozen ​14 days
Rejection Criteria
Gross Lipemia
Interference
Elevations in serum IgG4 concentrations are not specific to IgG4-related disease; they are also found in disorders such as multicentric Castleman disease, allergic disorders, Churg-Strauss syndrome, sarcoidosis, and a large number of other conditions.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​ ​Monday through Saturday ​Same day/1 day ​Nephelometry
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
0-<5 months: < or =19.8 mg/dL
5-<9 months: < or =20.8 mg/dL
9-<15 months: < or =22.0 mg/dL
15-<24 months: < or =23.0 mg/dL
2-<4 years: 0.4-49.1 mg/dL
4-<7 years: 0.8-81.9 mg/dL
7-<10 years: 1.0-108.7 mg/dL
10-<13 years: 1.0-121.9 mg/dL
13-<16 years: 0.7-121.7 mg/dL
16-<18 years: 0.3-111.0 mg/dL
> or =18 years: 2.4-121.0 mg/dL
Interpretation
Elevated levels of IgG4 are consistent with, but not diagnostic of, IgG4-related disease.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​82787 ​ ​ ​ ​
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​1 mL ​0.5 mL ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​14 days
​Ambient ​14 days
​Frozen ​14 days
Rejection Criteria
Gross Lipemia
Interference
Elevations in serum IgG4 concentrations are not specific to IgG4-related disease; they are also found in disorders such as multicentric Castleman disease, allergic disorders, Churg-Strauss syndrome, sarcoidosis, and a large number of other conditions.
Useful For
Supporting the diagnosis of IgG4-related disease
Reference Range Information
0-<5 months: < or =19.8 mg/dL
5-<9 months: < or =20.8 mg/dL
9-<15 months: < or =22.0 mg/dL
15-<24 months: < or =23.0 mg/dL
2-<4 years: 0.4-49.1 mg/dL
4-<7 years: 0.8-81.9 mg/dL
7-<10 years: 1.0-108.7 mg/dL
10-<13 years: 1.0-121.9 mg/dL
13-<16 years: 0.7-121.7 mg/dL
16-<18 years: 0.3-111.0 mg/dL
> or =18 years: 2.4-121.0 mg/dL
Interpretation
Elevated levels of IgG4 are consistent with, but not diagnostic of, IgG4-related disease.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Medical Laboratories​ ​Monday through Saturday ​Same day/1 day ​Nephelometry
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​82787 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.