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26007 Surgical Pathology, HPV High Risk DNA ISH (HPVHR)

Surgical Pathology, HPV High Risk DNA ISH (HPVHR)
Test Code: HPVHRSO
Synonyms/Keywords

​HPV (Human Papillomavirus)
Papillomavirus
HPVHR

Test Components
​Human Papillomavirus (HPV) high risk E6/E7 will be performed at the discretion of the Mayo pathologist.
Useful For
​Detection of human papillomavirus DNA from high-risk genotypes (16, 18, 31, 33 and 51)
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Formalin-fixed, paraffin-embedded tissue block ​ ​ ​Entire block ​ ​
​​5 unstained glass, positively charged slides with 5 (+ or - 1)-microns formalin-fixed, paraffin-embedded tissue ​ ​ ​5 slides ​ ​
Collection Processing Instructions
​A  pathology/diagnostic report and a brief history are required.
Acceptable Specimen Types
​10% neutral buffered formalin fixed tissue specimen/ paraffin embedded tissue block
Specimen Stability Information
Specimen Type Temperature Time
​Tissue Slides Ambient ​ Indefinite
​10% Neutral Buffered Formalin Fixed Tissue Specimen ​ Ambient (preferred) ​ 6 months
​Refrigerate ​1 month
Rejection Criteria
​Nonformalin fixed tissue
​Nonparaffin embedded tissue
​Noncharged slides
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Friday ​5 days ​In situ hybridization on sections of paraffin-embedded tissue.(Unpublished Mayo method)
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
See Report
Interpretation
​This test, when not accompanied by a pathology consultation request, will be answered as either positive or negative. If additional interpretation or analysis is needed, request 70012 / Pathology Consultation along with this test.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​88365 ​ ​ ​ ​
Synonyms/Keywords

​HPV (Human Papillomavirus)
Papillomavirus
HPVHR

Test Components
​Human Papillomavirus (HPV) high risk E6/E7 will be performed at the discretion of the Mayo pathologist.
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Formalin-fixed, paraffin-embedded tissue block ​ ​ ​Entire block ​ ​
​​5 unstained glass, positively charged slides with 5 (+ or - 1)-microns formalin-fixed, paraffin-embedded tissue ​ ​ ​5 slides ​ ​
Collection Processing
​A  pathology/diagnostic report and a brief history are required.
Acceptable Specimen Types
​10% neutral buffered formalin fixed tissue specimen/ paraffin embedded tissue block
Specimen Stability Information
Specimen Type Temperature Time
​Tissue Slides Ambient ​ Indefinite
​10% Neutral Buffered Formalin Fixed Tissue Specimen ​ Ambient (preferred) ​ 6 months
​Refrigerate ​1 month
Rejection Criteria
​Nonformalin fixed tissue
​Nonparaffin embedded tissue
​Noncharged slides
Useful For
​Detection of human papillomavirus DNA from high-risk genotypes (16, 18, 31, 33 and 51)
Test Components
​Human Papillomavirus (HPV) high risk E6/E7 will be performed at the discretion of the Mayo pathologist.
Reference Range Information
See Report
Interpretation
​This test, when not accompanied by a pathology consultation request, will be answered as either positive or negative. If additional interpretation or analysis is needed, request 70012 / Pathology Consultation along with this test.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Friday ​5 days ​In situ hybridization on sections of paraffin-embedded tissue.(Unpublished Mayo method)
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​88365 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.