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26040 Iodine, Serum (IOD)

Iodine, Serum (IOD)
Test Code: IODSO
Useful For
​Determination of iodine overload
Monitoring iodine levels in individuals taking iodine-containing drugs
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum Plain, royal blue-top top Vacutainer plastic trace element blood collection tube​ ​ ​1.0 mL ​0.3 mL ​
Collection Processing Instructions
​Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.
 
Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​21 days
​Ambient ​21 days
​Frozen ​21 days
Rejection Criteria
Gross icterus
Interference
​There are no known analytical interferences with this procedure.
Administration of iodine-containing contrast media will yield elevated results.
High concentrations of gadolinium are known to interfere with most metals tests. If gadolinium-containing contrast media has been administered, a specimen should not be collected for 48 hours.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories (Rochester) ​Monday, Tuesday, Wednesday, Friday ​3 days ​Inductively coupled plasma-mass spectrometer
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories ​40-92 ng/mL
Interpretation
Values between 80 ng/mL and 250 ng/mL have been reported to indicate hyperthyroidism. Values >250 ng/mL may indicate iodine overload.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83789 ​ ​1 ​ ​
Ordering Applications
Ordering Application Description
​Centricity ​Iodine, Serum (IOD)
​Cerner ​Iodine, Serum (IOD)
​COM ​Iodine, Serum (IOD)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum Plain, royal blue-top top Vacutainer plastic trace element blood collection tube​ ​ ​1.0 mL ​0.3 mL ​
Collection Processing
​Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.
 
Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​21 days
​Ambient ​21 days
​Frozen ​21 days
Rejection Criteria
Gross icterus
Interference
​There are no known analytical interferences with this procedure.
Administration of iodine-containing contrast media will yield elevated results.
High concentrations of gadolinium are known to interfere with most metals tests. If gadolinium-containing contrast media has been administered, a specimen should not be collected for 48 hours.
Useful For
​Determination of iodine overload
Monitoring iodine levels in individuals taking iodine-containing drugs
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories ​40-92 ng/mL
Interpretation
Values between 80 ng/mL and 250 ng/mL have been reported to indicate hyperthyroidism. Values >250 ng/mL may indicate iodine overload.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories (Rochester) ​Monday, Tuesday, Wednesday, Friday ​3 days ​Inductively coupled plasma-mass spectrometer
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83789 ​ ​1 ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.